Miss. Marta Ferran Marqués

Miss. Marta Ferran Marqués |Clyto Access

Autonomous University of Barcelona, Spain

Speaker

Expertise: nanoparticle composites

Biography:

Marta Ferran is currently completing an MSc in Aerospace Materials at Cranfield University and has recently graduated in Nanoscience and Nanotechnology. After two years of her hard work as a researcher at Gnm3 group in Barcelona, she has strong analytical, communication and teamwork skills. She is familiar with the synthesis and characterisation of materials. She had the chance to get involved into three different projects. In the first one, she actively contributed to the research on electrodeposited spatio-temporal cobalt-indium (Co-In) alloys, which resulted in a recent publication in Materials & Design (I.F. 3.997): I. Golvano-Escobal, J. de Dios Sirvent, M. Ferran-Marqués, S. Suriñach, M. D. Baró, S. Pané, J. Sort, E. Pellicer. Cross-sectioning spatio-temporal Co-In electrodeposits: disclosing a magnetically-patterned nanolaminated structure. Mater. Des. 114 (2017) 202-207. In the second one, she focused on the preparation of porous iron-manganese (FeMn) membranes by sputtering, the characterization of their physical properties, and their performance as drug carrier platforms. This research also resulted in the latest article in Nanomaterials (I.F. 3.553): ‘J. Fornell, J. Soriano, M. Guerrero, J. de Dios Sirvent, M. Ferran-Marqués, E. Ibáñez, L. Barrios, M. D. Baró, S. Suriñach, C. Nogués, J. Sort, E. Pellicer. Biodegradable FeMnSi Sputter- Coated Macroporous Polypropylene Membranes for the Sustained Release of Drugs. Nanomaterials 7 (2017) 155’. 
Finally, she has devoted to the preparation of metal matrix/nanoparticle composites by electrodeposition and the study of the resulting nanomechanical properties.

Presentation:

Title: Development of FeMnSi-coated polypropylene membranes as potential micro-robotic platforms for drug delivery applications

Abstract:

Targeted delivery of therapeutics represents a promising alternative or supplement to traditional cancer chemotherapies. In the past decade, novel strategies have been devised to directly target tumour tissues while avoiding side effects due to systemic exposure to anti-cancer drugs. Polymeric materials are particularly amenable for drug delivery purposes because they offer an interesting combination of properties, such as diffusivity, permeability, biocompatibility, and solubility. The diffusion, dissolution, permeation, and swelling characteristics of polymers have been exploited to obtain a constant release of entrapped molecules. For the therapeutic delivery of molecules, the polymer can act as a passive entity that hosts the drug and ensures its sustained release (e.g., subcutaneous patch) or can be envisioned as a micro-robotic platform that enables both transport of the molecule to the target site and its subsequent release. Guidance of micro-robotic platforms under the action of magnetic fields is a promising approach because they are capable of penetrating most materials with minimal interaction, and are almost harmless to human beings even at relatively high field strengths (provided no high-frequency AC magnetic fields are used). In this work, magnetic organic-inorganic hybrids consisting of a magnetic material, FeMnSi, and a porous polymeric membrane, polypropylene (PP), were manufactured and subsequently loaded with Transferrin-Alexa Fluor 488 (Tf-AF488) to investigate its distribution within the porous skeleton, its kinetics of release, and its cellular uptake.

Related Conferences :

2nd world summit on Nanotechnology and Nanomedicine Research